Tissue Morphogenesis and Repair Unit

We use animal model systems, Drosophila and Zebrafish to study molecular, cellular and developmental processes that are relevant for Biomedical Science, in particular tissue morphogenesis and repair. We use Drosophila to study tissue dynamics and adhesion in a simple model of epithelial wound repair and in dorsal closure, an embryonic morphogenetic movement that has striking similarities to wound healing. Presently, our group is extending those studies and investigating the mechanisms that regulate the recruitment of macrophage-like blood cells (hemocytes) to wound sites. We have also initiated recently a new research programme to investigate wound healing and tissue regeneration using the Zebrafish as a model system. In the future we would like to translate the results of our model system studies to other vertebrates and if possible to humans.

Journal Club Session I

Journal Club Session II (Current)

Tissue Regeneration and Stem Cells Forum

Instituto de Medicina Molecular,
Av Prof Egas Moniz,
Edificio Egas Moniz, Room P3B35,
1649-028 Lisboa, Portugal
Tel: 21 7999516 ext 47355
Fax: 21 7999504