Ex vivo expansion conditions of embryonic stem cells and neural stem cells, namely, the optimization of the operational conditions for this purpose, and their differentiation into neural lineages. Also interested in the transcriptome analysis of different neural precursor cell populations.
Post-doctoral researcher (April 2006 – currently) Post-doctoral researcher at the Developmental Biology Unit, “Instituto de Medicina Molecular”, “Faculdade de Medicina de Lisboa”, since April 2006. Supervised by Prof. Domingos Henrique.
Ph.D. in Biotechnology (January 2002 – March 2006) Ph.D. project on “Ex vivo Expansion and Neural Differentiation of mouse Embryonic Stem Cells”, developed at the BioEngineering Research Group, Instituto Superior Técnico, Universidade Técnica de Lisboa. Supervised by: Prof. Joaquim M.S. Cabral and Prof. Domingos Henrique.
Graduation in Chemical Engineering (1996 – 2001) Five-year graduation course in Chemical Engineering, at Instituto Superior Técnico, Universidade Técnica de Lisboa, Lisbon, Portugal.
Abranches E, Silva M, Pradier L, Shultz H, Hummel O, Henrique D, Bekman E, Neural Differentiation of Embryonic Stem Cells in vitro: a Road Map to Neurogenesis in the Embryo, PlosOne, 4(7): e6286 (2009)
Fernandes A, Falcão AS, Abranches E, Bekman E, Henrique D, Lanier L, Brites D, Uncovering the potential neurodevelopmental deficits in a common neonatal condition such as jaundice, Developmental Neurobiology, 69(9): 568-582 (2009)
Abranches E, Bekman E, Henrique D, Cabral JMS, Expansion of mouse embryonic stem cells on microcarriers, Biotechnology & Bioengineering, 96: 1211-21 (2007)
Abranches E, O’Neill A, Cabral JMS, Schaffer DV, Development of quantitative PCR protocols to analyze neural progenitor cell culture state, Biotecnology and Applied Biochemistry, 44: 1-8 (2006)
Abranches E, Bekman E, Henrique D, Cabral JMS, Expansion and neural differentiation of embryonic stem cells in adherent and suspension cultures, Biotechnology Letters, 25: 725-730 (2003)
Instituto de Medicina Molecular,
Av. Prof. Egas Moniz,
Edifício Egas Moniz, Room P3B35,
1649-028 Lisboa, Portugal
Tel: +351 21 7999516
Fax: +351 21 7999504